Motif ID: TAL1_TCF{3,4,12}.p2

Z-value: 0.423


Transcription factors associated with TAL1_TCF{3,4,12}.p2:

Gene SymbolEntrez IDGene Name
TAL1 6886 T-cell acute lymphocytic leukemia 1
TCF12 6938 transcription factor 12
TCF3 6929 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
TCF4 6925 transcription factor 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TCF4chr18_-_514063590.572.2e-02Click!
TCF3chr19_-_16033250.322.3e-01Click!
TAL1chr1_-_474680290.107.2e-01Click!
TCF12chr15_+_552989080.107.2e-01Click!


Activity profile for motif TAL1_TCF{3,4,12}.p2.

activity profile for motif TAL1_TCF{3,4,12}.p2


Sorted Z-values histogram for motif TAL1_TCF{3,4,12}.p2

Sorted Z-values for motif TAL1_TCF{3,4,12}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TAL1_TCF{3,4,12}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_46967360 0.305 NM_001170460
CDK16
cyclin-dependent kinase 16
chr10_-_14090459 0.290 FRMD4A
FERM domain containing 4A
chr6_-_42798286 0.288 NM_000322
PRPH2
peripherin 2 (retinal degeneration, slow)
chr9_-_135435165 0.253 NM_001080515
FAM163B
family with sequence similarity 163, member B
chr17_-_53761119 0.229 NM_004758
NM_024418
BZRAP1

benzodiazapine receptor (peripheral) associated protein 1

chr8_-_81155564 0.217 NM_001025252
TPD52
tumor protein D52
chr10_+_80743769 0.211 ZMIZ1
zinc finger, MIZ-type containing 1
chr3_+_196933481 0.210 MUC20
mucin 20, cell surface associated
chrX_+_38096679 0.208 NM_000531
OTC
ornithine carbamoyltransferase
chr1_+_116181927 0.176 NHLH2
nescient helix loop helix 2
chr6_-_41811916 0.175 NM_001167827
TFEB
transcription factor EB
chr2_-_183095308 0.175 NM_005019
NM_001003683
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr17_-_36409632 0.173 NM_031959
KRTAP3-2
keratin associated protein 3-2
chr17_+_38256710 0.170 NM_003734
AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr6_-_29451042 0.163 NM_030959
OR12D3
olfactory receptor, family 12, subfamily D, member 3
chr1_+_221168388 0.163 NM_032890
DISP1
dispatched homolog 1 (Drosophila)
chr1_-_23393808 0.162 NM_000864
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D
chr19_+_15765760 0.159 NM_001004466
OR10H5
olfactory receptor, family 10, subfamily H, member 5
chr16_-_29817841 0.154 NM_001114099
NM_001114100
NM_012410
NM_201575
SEZ6L2



seizure related 6 homolog (mouse)-like 2



chr5_+_38439399 0.154 NM_182798
NM_182799
EGFLAM

EGF-like, fibronectin type III and laminin G domains

chr17_+_40594046 0.152 NM_144608
HEXIM2
hexamthylene bis-acetamide inducible 2
chr2_+_169367345 0.151 NM_001039724
NM_001171632
NM_052946
NOSTRIN


nitric oxide synthase trafficker


chr14_-_80934523 0.150 NM_033104
STON2
stonin 2
chr16_-_29818334 0.150 SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr19_+_15699833 0.149 NM_013939
OR10H2
olfactory receptor, family 10, subfamily H, member 2
chr4_-_152368492 0.142 SH3D19
SH3 domain containing 19
chrX_+_55951280 0.138


chr7_-_41709191 0.136 NM_002192
INHBA
inhibin, beta A
chr7_+_138695236 0.136 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr19_+_17499064 0.136 FAM129C
family with sequence similarity 129, member C
chr7_+_149104063 0.135 NM_198455
SSPO
SCO-spondin homolog (Bos taurus)
chr10_+_44726635 0.134 NM_001123376
TMEM72
transmembrane protein 72
chr11_-_62445587 0.130 NM_000738
CHRM1
cholinergic receptor, muscarinic 1
chr1_-_203657803 0.130 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr2_-_183611470 0.126 NM_013436
NM_205842
NCKAP1

NCK-associated protein 1

chr21_-_33107813 0.123 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr2_-_158008763 0.122 NM_004288
CYTIP
cytohesin 1 interacting protein
chr1_+_207926172 0.122 NM_181755
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr1_-_33585848 0.121


chr21_+_29439768 0.120 C21orf7
chromosome 21 open reading frame 7
chrX_+_85404626 0.119 NM_001139515
DACH2
dachshund homolog 2 (Drosophila)
chr1_-_149004852 0.118 CTSS
cathepsin S
chr17_+_38256886 0.117


chr1_-_205272619 0.116 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr7_+_138695209 0.116 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr7_+_75977680 0.113 NM_030570
NM_182684
UPK3B

uroplakin 3B

chr7_+_138695537 0.113 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr11_-_62445308 0.107 CHRM1
cholinergic receptor, muscarinic 1
chr2_-_151854619 0.105 NM_004688
NMI
N-myc (and STAT) interactor
chr1_-_176205672 0.102 NM_033127
SEC16B
SEC16 homolog B (S. cerevisiae)
chr1_-_144426918 0.102 NM_007053
CD160
CD160 molecule
chr15_+_55298908 0.100 NM_207040
TCF12
transcription factor 12
chrX_-_110400406 0.099 NM_014289
CAPN6
calpain 6
chr9_+_114376709 0.095 KIAA1958
KIAA1958
chr6_-_29431950 0.095 NM_030876
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr7_+_138695241 0.090 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr6_+_36318922 0.090 NM_173676
NM_001145716
PNPLA1

patatin-like phospholipase domain containing 1

chrX_-_19598912 0.089 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr7_+_94953148 0.087 NM_016116
NM_145872
ASB4

ankyrin repeat and SOCS box containing 4

chrX_+_102918409 0.087 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr12_-_46405477 0.086 NM_001172439
NM_001172440
NM_006025
ENDOU


endonuclease, polyU-specific


chr4_-_20594645 0.086 KCNIP4
Kv channel interacting protein 4
chr4_+_73123712 0.085 NM_001144756
NM_053036
NPFFR2

neuropeptide FF receptor 2

chr7_+_129807467 0.085 NM_001868
CPA1
carboxypeptidase A1 (pancreatic)
chr1_+_50342168 0.084 NM_001144776
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr1_+_54786394 0.082 NM_015547
NM_147161
ACOT11

acyl-CoA thioesterase 11

chrX_-_33267646 0.082 NM_000109
DMD
dystrophin
chr3_-_44527122 0.078 ZNF852
zinc finger protein 852
chr2_+_33213111 0.077 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chrX_+_46825179 0.075 RGN
regucalcin (senescence marker protein-30)
chr15_+_72687765 0.075 NM_003992
CLK3
CDC-like kinase 3
chr2_-_133256097 0.075 NCKAP5
NCK-associated protein 5
chr22_+_20880112 0.075


chr17_-_44641741 0.075 NM_031498
NM_001198755
NM_001198756
GNGT2


guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2


chr11_-_5212168 0.073 NM_000519
HBD
hemoglobin, delta
chrX_+_102918453 0.073 PLP1
proteolipid protein 1
chr8_+_21967008 0.073 NM_001114137
EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr3_-_44527083 0.071 ZNF852
zinc finger protein 852
chrX_-_46503415 0.071 NM_032591
SLC9A7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr1_+_92405196 0.070 NM_015237
KIAA1107
KIAA1107
chrX_-_15593074 0.070 NM_020665
TMEM27
transmembrane protein 27
chrX_-_46503540 0.069 SLC9A7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr1_-_199613427 0.069 NM_000364
NM_001001430
NM_001001431
NM_001001432
TNNT2



troponin T type 2 (cardiac)



chr7_+_138695144 0.068 NM_016019
LUC7L2
LUC7-like 2 (S. cerevisiae)
chr6_-_169392771 0.066


chr7_+_127020924 0.066 NM_020369
FSCN3
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)
chr1_+_32489426 0.064 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr1_-_149004879 0.063 CTSS
cathepsin S
chr22_+_38652555 0.060 GRAP2
GRB2-related adaptor protein 2
chr12_-_55404530 0.060 NACA
nascent polypeptide-associated complex alpha subunit
chr17_-_10362583 0.060 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chrX_+_128741562 0.060 NM_018990
SASH3
SAM and SH3 domain containing 3
chrX_+_138440560 0.059 NM_000133
F9
coagulation factor IX
chr5_+_53787187 0.059 NM_006308
HSPB3
heat shock 27kDa protein 3
chr11_-_4827013 0.058 NM_001004758
OR51S1
olfactory receptor, family 51, subfamily S, member 1
chr3_-_188936941 0.058 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr22_+_19601940 0.057 CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chrX_+_48127911 0.057 NM_001034832
NM_001040612
NM_005636
NM_175729
SSX4B

SSX4

synovial sarcoma, X breakpoint 4B

synovial sarcoma, X breakpoint 4

chr12_-_121753795 0.057 NM_177551
GPR109A
G protein-coupled receptor 109A
chr11_-_74478405 0.056 NM_001005285
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chrX_+_102918089 0.055 NM_001128834
PLP1
proteolipid protein 1
chr3_-_196792274 0.055 NM_001647
APOD
apolipoprotein D
chr9_-_14712669 0.054 NM_005454
CER1
cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)
chrX_-_47941142 0.054 NM_021015
NM_175723
SSX5

synovial sarcoma, X breakpoint 5

chr6_-_27988152 0.054 NM_033057
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr2_+_151922350 0.053 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr14_+_19414230 0.053 NM_001005501
OR4K2
olfactory receptor, family 4, subfamily K, member 2
chr4_-_77176163 0.053 NM_005409
CXCL11
chemokine (C-X-C motif) ligand 11
chr3_+_113200696 0.053 NM_001008273
TAGLN3
transgelin 3
chr8_-_11966664 0.053 NM_001195257
NM_001037804
LOC100133267
DEFB130
defensin, beta 130-like
defensin, beta 130
chr11_-_57752923 0.052 NM_001004471
OR10Q1
olfactory receptor, family 10, subfamily Q, member 1
chr19_-_44060729 0.052 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr11_-_66431910 0.052 NM_022172
PC
pyruvate carboxylase
chrX_-_110400321 0.052 CAPN6
calpain 6
chr17_-_59342319 0.052 NM_001318
NM_022579
NM_022580
NM_022581
CSHL1



chorionic somatomammotropin hormone-like 1



chr11_+_72658586 0.051 NM_176798
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr17_+_45617676 0.051


chr10_+_85923473 0.051 NM_207373
C10orf99
chromosome 10 open reading frame 99
chr1_-_149004916 0.050 NM_004079
CTSS
cathepsin S
chr1_+_156842852 0.050 NM_001004478
OR10Z1
olfactory receptor, family 10, subfamily Z, member 1
chr16_-_79811475 0.050 NM_001076780
NM_052892
PKD1L2

polycystic kidney disease 1-like 2

chr5_-_88235624 0.050 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr5_-_158690047 0.050 NM_002187
IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
chr22_+_43451600 0.049 PRR5
proline rich 5 (renal)
chr5_+_173405298 0.049 NM_015980
HMP19
HMP19 protein
chr9_+_95886625 0.048 PTPDC1
protein tyrosine phosphatase domain containing 1
chr12_-_129568362 0.047 NM_015347
RIMBP2
RIMS binding protein 2
chr8_-_86441115 0.047 NM_001164830
CA1
carbonic anhydrase I
chr3_+_9933763 0.046 NM_032732
NM_153460
NM_153461
IL17RC


interleukin 17 receptor C


chr8_-_142586487 0.046 NM_207414
FLJ43860
FLJ43860 protein
chr19_-_14853166 0.045 NM_030901
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr17_-_74244539 0.045


chr19_+_56452775 0.044 NM_173635
C19orf75
chromosome 19 open reading frame 75
chr2_-_96320185 0.044 SNRNP200
small nuclear ribonucleoprotein 200kDa (U5)
chrX_+_123307812 0.043 NM_001114937
NM_002351
SH2D1A

SH2 domain containing 1A

chr1_+_33003814 0.043 NM_001198972
NM_001198973
KIAA1522

KIAA1522

chr21_+_38550739 0.042 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr2_+_108360798 0.042 NM_006588
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr2_-_55131124 0.042 RTN4
reticulon 4
chr9_+_95886558 0.042 NM_152422
PTPDC1
protein tyrosine phosphatase domain containing 1
chr2_-_55130925 0.042 RTN4
reticulon 4
chr2_-_55131157 0.041 RTN4
reticulon 4
chr1_+_158063278 0.040 SLAMF8
SLAM family member 8
chr12_+_61240542 0.040 MON2
MON2 homolog (S. cerevisiae)
chr6_-_41811323 0.040 TFEB
transcription factor EB
chr1_+_22835684 0.040 NM_015991
C1QA
complement component 1, q subcomponent, A chain
chr17_-_1037312 0.039 NM_001159746
ABR
active BCR-related gene
chr2_-_55131176 0.039 RTN4
reticulon 4
chr16_+_4546491 0.038 NM_001145011
LOC342346
hypothetical protein LOC342346
chrX_-_2896285 0.038 ARSE
arylsulfatase E (chondrodysplasia punctata 1)
chrX_-_55074125 0.038 NM_000032
NM_001037967
NM_001037968
ALAS2


aminolevulinate, delta-, synthase 2


chr15_+_38886546 0.038 NM_001077268
ZFYVE19
zinc finger, FYVE domain containing 19
chr22_-_16127520 0.037 CECR3
cat eye syndrome chromosome region, candidate 3
chrX_-_55037235 0.037 NM_002625
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr1_-_151280201 0.036 NM_006945
SPRR2D
small proline-rich protein 2D
chr1_+_33003847 0.036 KIAA1522
KIAA1522
chr1_-_202432165 0.035 NM_002256
KISS1
KiSS-1 metastasis-suppressor
chr14_-_93919305 0.035 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr19_-_40996040 0.035 NM_021232
PRODH2
proline dehydrogenase (oxidase) 2
chr16_+_21623784 0.035 NM_170664
OTOA
otoancorin
chrX_+_128741578 0.035 SASH3
SAM and SH3 domain containing 3
chr1_-_199613406 0.035 TNNT2
troponin T type 2 (cardiac)
chr2_-_55131096 0.035 RTN4
reticulon 4
chr10_-_121286034 0.034 NM_002925
RGS10
regulator of G-protein signaling 10
chr1_-_108588186 0.034 NM_001143989
NBPF4
NBPF6
neuroblastoma breakpoint family, member 4
neuroblastoma breakpoint family, member 6
chr8_-_72436519 0.034 EYA1
eyes absent homolog 1 (Drosophila)
chr17_+_6599879 0.034 NM_017523
NM_199139
XAF1

XIAP associated factor 1

chr6_+_29249289 0.034 NM_030905
OR2J2
olfactory receptor, family 2, subfamily J, member 2
chr7_-_44071640 0.034 NM_000290
PGAM2
phosphoglycerate mutase 2 (muscle)
chr10_+_71482362 0.033 NM_018649
H2AFY2
H2A histone family, member Y2
chr7_+_104539548 0.033 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr11_-_123130435 0.033 NM_001005188
OR6X1
olfactory receptor, family 6, subfamily X, member 1
chr11_+_5367182 0.033 NM_001004756
OR51M1
olfactory receptor, family 51, subfamily M, member 1
chr1_-_16006779 0.032 NM_001089591
UQCRHL
ubiquinol-cytochrome c reductase hinge protein-like
chr6_-_32227695 0.032 NM_030651
PRRT1
proline-rich transmembrane protein 1
chr11_+_125000245 0.032 NM_001114121
NM_001114122
CHEK1

CHK1 checkpoint homolog (S. pombe)

chr8_-_12220195 0.032 NM_001195257
NM_001037804
LOC100133267
DEFB130
defensin, beta 130-like
defensin, beta 130
chr19_-_59438411 0.032 NM_024318
LILRB3
LILRA6
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chrX_-_111809929 0.032 NM_178175
LHFPL1
lipoma HMGIC fusion partner-like 1
chr19_+_51190535 0.032 CCDC61
coiled-coil domain containing 61
chr15_-_58706934 0.032 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr17_-_70053839 0.032 NM_006678
CD300C
CD300c molecule
chr5_+_173405343 0.032 HMP19
HMP19 protein
chr4_-_24523605 0.032 NM_001130726
CCDC149
coiled-coil domain containing 149
chr20_-_36191623 0.031 TGM2
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr2_-_97775300 0.031 TMEM131
transmembrane protein 131
chr16_+_11966464 0.031 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr5_+_67558217 0.031 NM_181523
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chrX_-_32340291 0.030 NM_004011
NM_004012
DMD

dystrophin

chr14_-_20179689 0.030 NM_001001968
OR6S1
olfactory receptor, family 6, subfamily S, member 1
chr1_+_50344550 0.030 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr7_+_143457083 0.030 NM_001001659
OR2A14
olfactory receptor, family 2, subfamily A, member 14
chr1_+_17817397 0.029 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr6_+_126143971 0.029 NCOA7
nuclear receptor coactivator 7
chr16_-_20246309 0.029 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chrX_-_74292800 0.029 NM_004299
ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr1_+_205328834 0.029 NM_001017365
NM_001017366
C4BPB

complement component 4 binding protein, beta

chr17_-_58237742 0.029 NM_001100875
MARCH10
membrane-associated ring finger (C3HC4) 10
chr9_-_135379888 0.029 NM_001080483
TMEM8C
transmembrane protein 8C
chr2_-_55130963 0.029 RTN4
reticulon 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.94 1.70e-13 GO:0007608 sensory perception of smell
4.65 2.35e-13 GO:0007606 sensory perception of chemical stimulus
3.20 5.84e-10 GO:0007600 sensory perception
2.36 5.99e-07 GO:0050877 neurological system process
2.11 4.39e-06 GO:0003008 system process
1.45 9.15e-06 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.44 2.54e-03 GO:0005886 plasma membrane
1.43 2.95e-03 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
5.18 7.61e-15 GO:0004984 olfactory receptor activity
3.08 4.97e-10 GO:0004930 G-protein coupled receptor activity
2.58 1.09e-09 GO:0004888 transmembrane receptor activity
2.22 2.51e-08 GO:0004872 receptor activity
1.99 3.82e-07 GO:0004871 signal transducer activity
1.99 3.82e-07 GO:0060089 molecular transducer activity